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[104] designed iron oxide-loaded liposomes decorated with phosphatidylserine (PS), a cell surface ligand displayed on apoptotic cells that triggers macrophage uptake and a subsequent phenotypic switch to an M2-like phenotype, enabling macrophage phenotype ma- nipulation as well as imaging and tracking by magnetic resonance
The act of neutrophil clearance by macrophages can induce the phenotypic switch of M1 macrophages to M2b, and lead to the resolution of inflammation (Filardy et al.
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